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Details Important Note This strain is homozygous for Cdh23ahl, the age related hearing loss 1 mutation, which on this background in progressive hearing loss with onset after 10 months of age. It is commonly used as a Black man looking for company tuesday purpose strain and background strain for the generation of congenics carrying both spontaneous and induced mutations.

Although this strain is refractory to many tumors, it is a permissive background for maximal expression of most mutations. This is a dominant trait.

The variation in aortic lesions found among various inbred strains has led to the identification of the existence of eight genes affecting atherosclerosis, Ath1 to Ath8. This deletion in the absence of the NNT protein, and is associated with impaired glucose homeostasis control and reduced insulin secretion.

Additionally, an intronic point deletion in Gabra2, which arose sometime between the early 's and 's, in decreased transcript and protein expression of this chloride Metropolis age fuck fish fsu area component in the brain.

Genetic background determines metabolic phenotypes in the mouse.

Genetic loci determining bone density in mice with diet-induced atherosclerosis. Variation in susceptibility to atherosclerosis among inbred strains of mice.

Development of a SNP genotyping panel for genetic monitoring of the laboratory mouse. Initial sequencing and comparative analysis of the mouse genome.